This study compared narrow versus wide initial margin protocols in Mohs micrographic surgery and their impact on the number of stages, tissue conservation, and cure rates. Results showed that narrow margins can be effective while preserving more tissue, though wider margins may reduce the number of stages required for certain tumor types.

Narrow initial excision margins in Mohs surgery can conserve tissue without compromising cure rates for well-defined tumors.

Wider initial margins may be appropriate for aggressive or poorly defined tumors to reduce the total number of Mohs stages.