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SLNB in MCC - Compliance with NCCN Guidelines: Rates and Predictors

MacArthur KM, Baumann BC, Sobanko JF, et al.
Dermatologic Surgery (2021)

Open AccessJC: March 2023

This study evaluated compliance with NCCN guidelines for sentinel lymph node biopsy (SLNB) in Merkel cell carcinoma and identified predictors of SLNB utilization. Results showed suboptimal guideline adherence, with patient age, tumor size, and facility type influencing whether SLNB was performed.

Take-Home Messages

  • •SLNB utilization in MCC remains below NCCN guideline recommendations, particularly in elderly patients and community settings.
  • •Efforts to improve SLNB compliance in MCC are warranted given its prognostic and therapeutic implications.
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Topic

Melanoma

Melanoma margins, SLNB, staging, Mohs for melanoma in situ

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Tumor Melanoma

Abstract

Sentinel lymph node biopsy (SLNB) has not been studied for invasive melanomas treated with Mohs micrographic surgery using frozen-section MART-1 immunohistochemical stains (MMS-IHC). The primary objective of this study was to assess the accuracy and compliance with National Comprehensive Cancer Network (NCCN) guidelines for SLNB in a cohort of patients who had invasive melanoma treated with MMS-IHC. This retrospective cohort study included all patients who had primary, invasive, cutaneous mel...

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Literature review only. This summary is an editorial interpretation and may not reflect the complete findings of the original publication. Always refer to the full-text article for clinical decision-making.