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Understanding Melanoma In Situ - Lentigo Maligna Surgical Approach (Abrantes et al.)

Abrantes T, Robbins A, Kahn B, et al.
Dermatologic Surgery (2023)

JC: November 2023

This study by Abrantes et al. reviewed the surgical approach to melanoma in situ of the lentigo maligna subtype, focusing on margin management and recurrence patterns. The paper highlighted the challenges of subclinical extension in lentigo maligna and supported staged excision techniques including Mohs surgery with melanocyte-specific immunostains.

Take-Home Messages

  • •Lentigo maligna frequently extends beyond clinically apparent borders, making margin-controlled excision techniques essential.
  • •Mohs surgery with MART-1 or other melanocyte immunostains improves margin accuracy and reduces recurrence in lentigo maligna.

Topic

Melanoma

Melanoma margins, SLNB, staging, Mohs for melanoma in situ

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Abstract

Malignant melanoma in-situ, lentigo maligna (MMIS-LM) can be successfully treated with several different surgical techniques; however, the literature is inconsistent in defining them. To comprehensively define and describe the national guideline recommended surgical techniques used to treat MMIS-LM to help clarify and standardize this terminology to ensure compliance with the guidelines. A targeted literature review was performed from 1990 to 2022 focusing on articles that discussed the natio...

Literature review only. This summary is an editorial interpretation and may not reflect the complete findings of the original publication. Always refer to the full-text article for clinical decision-making.