This study evaluated complication rates and risk factors associated with interpolation flaps used in facial reconstruction after Mohs surgery. Overall complication rates were low, and the study identified factors such as smoking, anticoagulation, and flap location that influenced outcomes.

Interpolation flaps are generally safe for facial reconstruction with low complication rates when performed by experienced surgeons.

Modifiable risk factors such as smoking cessation and anticoagulation management should be addressed preoperatively to optimize interpolation flap outcomes.