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Processing of Adipose Tissue - Autologous Fat Grafting in Reconstruction

Shah NG, Qi B, Zhang D, et al.
Dermatologic Surgery (2026)

JC: April 2023

This study reviewed processing methods for autologous adipose tissue used in fat grafting for reconstructive purposes after Mohs surgery. The review compared centrifugation, filtration, and washing techniques, providing guidance on optimizing graft viability for volume restoration and contour correction.

Take-Home Messages

  • Autologous fat grafting is a viable option for volume restoration and contour correction after Mohs surgery.
  • Processing technique selection affects fat graft viability and long-term volume retention in reconstructive applications.

Topic

Reconstruction

Flaps, grafts, wound closure techniques after Mohs

Abstract

Traumatic soft tissue defects pose significant challenges for reconstruction due to tissue loss, impaired vascularity, and difficulties achieving durable coverage. Adipose tissue offers a practical autologous tissue source, and mechanically processed stromal vascular fraction (SVF)-enriched microfat can be prepared intraoperatively without enzymatic digestion. This study presents a standardized clinical protocol for harvesting autologous adipose tissue and processing it into SVF-enriched micr...

Literature review only. This summary is an editorial interpretation and may not reflect the complete findings of the original publication. Always refer to the full-text article for clinical decision-making.