This meta-analysis assessed the efficacy of photodynamic rejuvenation (PDR) for treating actinic keratoses. Pooled data demonstrated that PDR effectively reduces AK counts while providing additional cosmetic benefits including improved skin texture and pigmentation, supporting its dual therapeutic and aesthetic role.

Photodynamic therapy effectively treats actinic keratoses while simultaneously improving overall skin photodamage.

PDR can serve as both a therapeutic intervention for AK and an aesthetic treatment for photodamaged skin.