This study evaluated the use of Mohs micrographic surgery for invasive cutaneous melanoma, analyzing cure rates, recurrence patterns, and outcomes compared with standard wide local excision. The data supported Mohs surgery as a viable option for melanoma, particularly at sites where tissue preservation is critical, with comparable oncologic outcomes.

Mohs surgery for invasive melanoma demonstrates comparable oncologic outcomes to wide local excision with superior tissue conservation.

MMS is especially advantageous for melanoma on the head and neck where standard excision margins would result in significant morbidity.