This concordance study by Juhasz et al. examined the agreement between clinical margin estimation and final pathological margins in cSCC excisions. The findings revealed that clinical margins frequently underestimate true tumor extent, reinforcing the value of margin-controlled excision techniques.

Clinical margin estimation frequently underestimates true pathological tumor extent in cSCC.

Margin-controlled excision techniques like Mohs surgery are superior to clinical estimation for ensuring complete tumor removal.