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Surgical Margins of Non-Melanoma Skin Cancers - Updated Analysis

Russomanno K, Abdel Azim S, Patel VA
Dermatologic Surgery (2023)

Open AccessJC: March 2025

This updated analysis reviewed recommended surgical margins for non-melanoma skin cancers, synthesizing data from multiple studies on margin adequacy for BCC and SCC. The review provided evidence-based guidance on optimal excision margins to balance complete tumor clearance with tissue conservation.

Take-Home Messages

  • •Standard surgical margins for NMSC should be guided by tumor type, histologic subtype, and anatomic location.
  • •Margin-controlled techniques like Mohs surgery remain the gold standard for high-risk NMSC when complete margin assessment is needed.
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Topic

Melanoma

Melanoma margins, SLNB, staging, Mohs for melanoma in situ

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Tumor Melanoma

Abstract

Non-melanoma skin cancers (NMSCs) are the most common cancers worldwide and may be associated with significant morbidity and mortality, especially in immunosuppressed populations. Successful management of NMSC must take primary, secondary and tertiary prevention strategies into consideration. In response to an improved understanding of the pathophysiology of NMSC and associated risk factors, multiple systemic and topical immunomodulatory drugs have been developed and integrated into clinical ...

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Literature review only. This summary is an editorial interpretation and may not reflect the complete findings of the original publication. Always refer to the full-text article for clinical decision-making.