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DFSP - SEER Database Analysis (Epidemiology & Outcomes)

Maghfour J, Genelin X, Olson J, et al.
Dermatologic Surgery (2024)

JC: December 2024

This SEER database analysis examined the epidemiology and outcomes of dermatofibrosarcoma protuberans (DFSP) in a large population-based cohort. The study characterized demographic patterns, treatment approaches, and survival outcomes, confirming the favorable prognosis of DFSP with appropriate surgical management.

Take-Home Messages

  • •DFSP has an excellent prognosis with low metastatic potential when treated with adequate surgical margins.
  • •Mohs surgery is associated with the lowest recurrence rates for DFSP and should be considered the treatment of choice when feasible.

Topic

Rare & Special Tumors

DFSP, AFX, sebaceous carcinoma, EMPD, MAC, and other rare entities

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Abstract

Limited information exists regarding the epidemiology, metastasis, and survival of dermatofibrosarcoma protuberans (DFSP). To measure DFSP incidence and assess metastasis and survival outcomes. Incidence rate, overall and DFSP-specific survival outcomes for primary DFSP tumors contained in the Surveillance, Epidemiology, and End Results (SEER) registry were analyzed via quasi-Poisson regression, Cox, and competing risk analyses. DFSP incidence rate was 6.25 (95% CI, 5.93-6.57) cases per milli...

Literature review only. This summary is an editorial interpretation and may not reflect the complete findings of the original publication. Always refer to the full-text article for clinical decision-making.