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Growing Adoption of IHC by Mohs Surgeons - National Medicare Trend Analysis

Gronbeck C, Feng H, Knackstedt T
Dermatologic Surgery (2024)

JC: September 2024

This national Medicare trend analysis documented the growing adoption of immunohistochemistry (IHC) by Mohs surgeons for margin assessment. The data showed a significant increase in IHC utilization over time, reflecting evolving practice patterns and the expanding role of IHC in Mohs surgery for melanoma and other tumors.

Take-Home Messages

  • •IHC utilization by Mohs surgeons has increased substantially, particularly for melanoma margin assessment with MART-1 and SOX-10.
  • •The growing adoption of IHC reflects the expanding scope of Mohs surgery beyond traditional NMSC indications.

Topic

Margin Assessment & IHC

Frozen section interpretation, MART-1, immunohistochemistry stains

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Mohs Technique

Abstract

Immunohistochemical (IHC) staining can be used alongside Mohs micrographic surgery to aid in margin assessment of subtle tumors, yet existing estimates of IHC utilization have primarily relied on survey or older data that lacks stratification. To characterize national IHC utilization trends by Mohs surgeons, stratifying by surgeon characteristics and modeling future adoption. Longitudinal analysis of 2014 to 2021 Medicare Public Use Files. In 2021, 158 of 2,058 Mohs surgeons (7.7%) used IHC a...

Literature review only. This summary is an editorial interpretation and may not reflect the complete findings of the original publication. Always refer to the full-text article for clinical decision-making.