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Rames MM, Rios-Duarte JA, Vidal NY
Dermatologic Surgery (2026)

JC: February 2025

This study evaluated the efficacy and safety of tranexamic acid (TXA) in reducing intraoperative bleeding during Mohs micrographic surgery. TXA administration was associated with reduced bleeding and improved visualization without significant adverse events, supporting its use as an adjunct hemostatic agent.

Take-Home Messages

  • Tranexamic acid can effectively reduce intraoperative bleeding during Mohs surgery without significant safety concerns.
  • TXA may be particularly beneficial in patients on anticoagulation or in vascular anatomic sites prone to excessive bleeding.

Topic

Perioperative Safety

Infection prevention, antibiotics, surgical safety protocols

Abstract

There is a paucity of literature investigating the use of liposomal bupivacaine (LB) in a dermatologic surgery setting. To identify the treatment characteristics and adverse events, including Local Anesthetic System Toxicity (LAST), in patients receiving perioperative LB. A retrospective chart review was performed at a single institution using an institutional database and key words "Exparel" or "liposomal bupivacaine." Patients ≥18 years old who received perioperative LB to the su...

Literature review only. This summary is an editorial interpretation and may not reflect the complete findings of the original publication. Always refer to the full-text article for clinical decision-making.