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TXA for Eyelid Surgery - Hemostasis in Periocular Procedures

Alamoudi A, Albishry AM, Alnabihi AN, et al.
Dermatologic Surgery (2025)

JC: June 2024

This study assessed the use of tranexamic acid for achieving hemostasis during eyelid and periocular surgical procedures. TXA demonstrated efficacy in reducing bleeding and improving the surgical field during delicate periocular reconstruction, with a favorable safety profile.

Take-Home Messages

  • •Tranexamic acid is effective for hemostasis in periocular surgery, improving visualization in this anatomically sensitive area.
  • •The favorable safety profile of TXA supports its use as an adjunctive hemostatic measure during eyelid reconstruction.

Topic

Reconstruction

Flaps, grafts, wound closure techniques after Mohs

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Abstract

To systematically evaluate evidence-based interventions aimed at reducing postoperative edema and ecchymosis in eyelid and periocular surgery, with the goal of improving patient outcomes and recovery. A systematic review of 29 randomized controlled trials (RCTs), involving 2,287 patients undergoing eyelid and periocular surgery, was conducted. A comprehensive search was performed across Embase, MEDLINE, Cochrane Central, and Google Scholar up to April 2025. Studies assessing interventions for...

Literature review only. This summary is an editorial interpretation and may not reflect the complete findings of the original publication. Always refer to the full-text article for clinical decision-making.