This randomized controlled trial evaluated whether adding 2-octyl cyanoacrylate (tissue adhesive) to intermediate layered closure improves aesthetic outcomes compared to intermediate closure alone. The study assessed the cosmetic and functional benefit of tissue adhesive as an adjunct to standard suture closure.

Adding tissue adhesive to standard layered closure may provide a modest cosmetic benefit and can serve as an alternative to superficial sutures.

2-Octyl cyanoacrylate offers the advantage of eliminating the need for suture removal when used as an epidermal closure substitute.