This study reviewed lidocaine dosing guidelines and safety considerations in dermatologic surgery, addressing maximum doses, toxicity risk factors, and clinical monitoring. The findings provided updated recommendations for safe lidocaine administration in both standard and extended dermatologic procedures.

Current evidence supports higher safe lidocaine doses than traditionally cited, particularly when used with epinephrine in dermatologic surgery.

Patient weight, hepatic function, and concurrent medications should be considered when calculating safe lidocaine doses.