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Assessing the Efficacy of Compression Therapy on Second Intention Wound Healing After Dermatologic Surgery (RCT)

Scherz LA, Walkosak CC, Renzi MA Jr, et al.
Dermatologic Surgery (2025)

JC: January 2026

This study assessed the efficacy of compression therapy in promoting second intention wound healing after dermatologic surgery. The analysis evaluated healing rates, cosmetic outcomes, and patient comfort with compression dressing protocols for wounds managed by secondary intention.

Take-Home Messages

•Compression therapy can enhance second intention wound healing rates and may improve cosmetic outcomes for appropriate surgical defects.
•Patient selection and wound location should guide the decision to incorporate compression therapy into second intention healing protocols.

Topic

Wound Healing

Second intention healing, wound management, scar optimization

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Abstract

Second intention healing (SIH) is an approach for lower extremity wounds after dermatologic surgery. Compression therapy has shown benefits in chronic venous insufficiency and venous ulcers, but its efficacy in promoting healing in lower extremity wounds healing by secondary intention is unclear. To evaluate the impact of compression stockings on wound healing time and postoperative complication rates in patients undergoing dermatologic surgery on the distal lower extremity with defects allow...